The Genomics Program advances programmable nucleic acid research on DNA and RNA through grammar-trained autoencoders of the hQVM AE suite, grounded in first principles. The models read biological sequences through the group-equivariant coordinate system and a formal algebra for nucleotides, codons, and codon-pair transitions derived from our CGM theory.
With training restricted to that coordinate system and no biological sequence in the corpus, every reproducible contact between readout and genomic structure that survives composition controls is a signature of the underlying physics. Even the faintest of those marks remains informative, and opens a concrete frontier for genomics.